FDA Review of Select Ortho-Phthalate Food Contact Substances as Chemically or Pharmacologically Related (CPR) Substances
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- Title
- FDA Review of Select Ortho-Phthalate Food Contact Substances as Chemically or Pharmacologically Related (CPR) Substances
- Posted
- May 27, 2026
- Comment period
- May 27, 2026 – Jul 27, 2026
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- Jul 26, 2026Comment from Kansal NyssaAnalysis pending📎 AttachmentRead comment →
- Jul 25, 2026Comment from Center for Food SafetySupportAdvocacy
The Center for Food Safety supports the FDA's review and conclusion that DEHP, DCHP, DIOP, and DINP should be grouped as chemically or pharmacologically related (CPR) substances. They commend the FDA's use of predictive modeling to address data gaps and their long-standing advocacy for better regulation of orthophthalates.
Read comment → - Jul 24, 2026Comment from Environmental Defense FundAnalysis pending📎 AttachmentRead comment →
- Jul 24, 2026Comment from Food Contact Safety CouncilSupportTrade association📎 Attachment
The Food Contact Safety Council (FCSC) supports the FDA's science-based post-market review and proposed chemically or pharmacologically related (CPR) grouping approach for ortho-phthalates. They advocate for a transparent, weight-of-evidence approach that considers toxicological similarity, current market use, and realistic exposure scenarios, specifically requesting the exclusion of DINP from the proposed grouping.
Read comment → - Jul 24, 2026Comment from Pew Charitable TrustsAnalysis pending📎 AttachmentRead comment →
- Jul 24, 2026Comment from The American Chemistry CouncilAnalysis pending📎 AttachmentRead comment →
- Jul 24, 2026Comment from Consumer Brands AssociationAnalysis pending📎 AttachmentRead comment →
- Jul 21, 2026Comment from Plastics Industry AssociationAnalysis pending📎 AttachmentRead comment →
- Jul 18, 2026Comment from Japan Plasticizers Industry AssociationOpposeTrade association📎 Attachment
The Japan Plasticizer Industry Association (JPIA) opposes the FDA's inclusion of four phthalic esters into the CPR substances category. They argue that the FDA's review failed to consider significant species differences in reproductive toxicity and metabolism, and they provide several studies to support their position.
Read comment → - Jul 14, 2026Comment from Food Packaging Forum FoundationAnalysis pending📎 AttachmentRead comment →