Comment submitted by People for the Ethical Treatment of Animals (PETA)

Summary: Adam Bettmann, representing PETA's Regulatory Toxicology Department, supports the EPA's integration of new approach methodologies (NAMs) in the risk evaluations for HHCB, phthalic anhydride, and dichlorobenzenes. He praises the use of AOP frameworks and transcriptomic data while urging the EPA to further transition toward human-relevant in vitro and in silico methods to reduce reliance on vertebrate animal testing.